Organization

The New England Journal of Medicine

Medical journal.

2 links, 0 backed by primary records. 2 more in open data

Connections 2

Report of the VIGOR trial of Vioxx, 2000 23 Nov 2000 Scholarship & press 1
Published in the Journal on 23 November 2000, as the editors' expression of concern says.
NEJM expression of concern on the VIGOR trial, 2005 29 Dec 2005 Scholarship & press 1

Timeline 2 dates

Proof 1 source

Expression of Concern: Bombardier et al., "Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis," N Engl J Med 2000;343:1520-8, The New England Journal of Medicine, 29 Dec 2005. Scholarship & press
The VIGOR study was designed primarily to compare gastrointestinal events in patients with rheumatoid arthritis randomly assigned to treatment with rofecoxib (Vioxx) or naproxen (Naprosyn), but data on cardiovascular events were also monitored.
Three myocardial infarctions, all in the rofecoxib group, were not included in the data submitted to the Journal.

Page history 1 change