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Report of the VIGOR trial of Vioxx, 2000
Report by Bombardier and others, published in the New England Journal of Medicine on 23 November 2000, comparing rofecoxib (Vioxx) with naproxen.
- Dates
- 23 Nov 2000
Connections 2
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author
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The New England Journal of Medicine
23 Nov 2000
Scholarship & press
1
Published in the Journal on 23 November 2000, as the editors' expression of concern says.
Timeline 2 dates
- 23 Nov 2000 Report of the VIGOR trial of Vioxx, 2000
- 23 Nov 2000 The New England Journal of Medicine authored Report of the VIGOR trial of Vioxx, 2000
Proof 1 source
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Expression of Concern: Bombardier et al., "Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis," N Engl J Med 2000;343:1520-8, The New England Journal of Medicine, 29 Dec 2005.
Scholarship & press
The VIGOR study was designed primarily to compare gastrointestinal events in patients with rheumatoid arthritis randomly assigned to treatment with rofecoxib (Vioxx) or naproxen (Naprosyn), but data on cardiovascular events were also monitored.
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